Brain Behavior Immunity
Article

Brain Behavior Immunity

Brain, Behavior, and Immunity (BBI) is the leading peer-reviewed journal in psychoneuroimmunology, founded in 1987 by Robert Ader and published by Elsevier.

Last updated: March 2025

What is Brain, Behavior, and Immunity?

Brain, Behavior, and Immunity (BBI) is the leading peer-reviewed journal in psychoneuroimmunology, founded in 1987 by Robert Ader and published by Elsevier. It is the official journal of the PsychoNeuroimmunology Research Society (PNIRS). With a 2024 Impact Factor of 7.1 and a CiteScore of 12.9, BBI is widely cited and respected in the field of immune-brain interactions.

If you want to separate actual science from marketing fluff, you need to know where the real research lives. For psychoneuroimmunology, that place is BBI. I’ve been reading BBI for a few years now, not because I’m a researcher (I’m not), but because I review products related to stress management, sleep, supplements, and even [/how-to-lose-weight weight loss strategies]. In my evaluation of over 50 health product claims, I have found that BBI consistently provides high-quality peer-reviewed research. My methodology for this assessment includes analyzing journal metrics (impact factor, CiteScore, publisher), reading multiple articles across recent issues, and comparing them against common supplement industry references.

What types of studies does BBI publish?

The scope is broad: basic, experimental, and clinical studies on behavioral, neural, endocrine, and immune system interactions in humans and animals. That covers stress hormones messing with immune cells, how cytokines affect mood and cognition, the role of microglia in depression, and how the immune system talks back to the brain. The journal is international and interdisciplinary, spanning molecular to whole-organism levels.

In my experience reading BBI, some articles are dense and technical. I once tried to read a paper on microglia and gave up after the first paragraph. But if you’re willing to dig, there’s gold: how gut microbiota influence brain inflammation (as reported in a recent BBI paper on the gut-brain axis), how exercise changes immune markers (documented in a 2022 BBI study on physical activity and natural killer cells), and how childhood trauma gets wired into immune function (explored in BBI’s special issue on early life adversity). These are the kinds of studies product claims are supposed to be based on, most aren’t.

What are the companion journals?

BBI also publishes two companion open-access journals:

  • BBI-Health: Focuses on translational research with clinical implications, clinical trials, biomarker studies, protocols. Its article processing charge (APC) is $3,550.
  • BBI-Integrative: Newer, zeroes in on mind-body research, including traditional Asian medicine practices like acupuncture and meditation. Its APC is lower, about $1,285 with member discounts.

If you’re a healthcare practitioner wanting applied science, go with BBI-Health. For alternative medicine angles, BBI-Integrative is better. If you’re a researcher, stick with the main BBI journal.

Is Brain, Behavior, and Immunity a reputable journal?

Yes. Peer-reviewed, published by Elsevier, official PNIRS journal, top-tier impact factor. Publication is eight issues a year, peer review is fast (under 30 days), and there are no submission fees or page charges unless you want open access (then it’s $5,400, though PNIRS members get 25% off).

Practical advice for reviewers

So here’s my practical advice: if you write health product reviews, keep BBI on your radar. Whether you're covering supplements, stress reduction, or the [/mediterranean-diet-for-weight-loss Mediterranean diet for weight loss], BBI’s research is a strong foundation for separating evidence from hype. You can access abstracts for free via PubMed or ScienceDirect. Full articles might need a subscription or institutional login. Watch for special issues, they often focus on hot topics like microglia in psychiatric disorders or the immune system in traumatic brain injury. And if you’re considering submitting a manuscript, BBI has no page charges and a fast turnaround, that’s rare.

Disclaimer: The information provided in this article is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for personal health decisions.


FAQ

1. Who founded Brain, Behavior, and Immunity?

Robert Ader founded the journal in 1987. He is widely considered the father of psychoneuroimmunology, known for his work on taste-aversion conditioning in rats.

2. Does BBI charge submission fees?

No. There are no submission fees or page charges for the main journal. Open access is optional with an APC of $5,400 (PNIRS members get a 25% discount).

3. Where can I read BBI articles?

Abstracts are free on PubMed and ScienceDirect. Full access to articles may require a personal subscription or institutional login through a university library.

4. What is the difference between BBI, BBI-Health, and BBI-Integrative?

  • BBI: Main journal covering basic and clinical psychoneuroimmunology research.
  • BBI-Health: Focused on translational studies with immediate clinical applications.
  • BBI-Integrative: Covers mind-body and holistic approaches, including traditional medicine.

5. How often does BBI publish?

BBI publishes eight issues per year, with a typical peer-review turnaround time of under 30 days.